Angel R Nebreda Selected Research

Mitogen-Activated Protein Kinase 14

2/2007	p38alpha MAP kinase as a sensor of reactive oxygen species in tumorigenesis.
2/2004	TAB3, a new binding partner of the protein kinase TAK1.
6/2002	Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity.

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Angel R Nebreda Research Topics

Disease

19	Neoplasms (Cancer) 11/2020 - 06/2002
8	Breast Neoplasms (Breast Cancer) 11/2018 - 01/2012
7	Carcinogenesis 01/2018 - 04/2006
4	Inflammation (Inflammations) 01/2022 - 09/2012
4	Neoplasm Metastasis (Metastasis) 11/2020 - 02/2012
3	Colonic Neoplasms (Colon Cancer) 01/2018 - 07/2014
3	Necrosis 10/2008 - 11/2003
2	Colorectal Neoplasms (Colorectal Cancer) 11/2020 - 01/2018
2	Cognitive Dysfunction 12/2019 - 01/2017
1	Lung Neoplasms (Lung Cancer) 01/2020
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2020
1	Ovarian Neoplasms (Ovarian Cancer) 01/2019
1	Alzheimer Disease (Alzheimer's Disease) 01/2019
1	Chromosomal Instability (Chromosome Stability) 11/2018
1	Ulcerative Colitis 01/2018
1	Colitis 01/2018
1	Anemia 01/2018
1	Intestinal Diseases (Diseases, Intestinal) 01/2018
1	Overweight 01/2018
1	Triple Negative Breast Neoplasms 01/2017
1	Neuroinflammatory Diseases 01/2017
1	Hypertrophy 01/2017
1	Aneuploidy (Aneuploid) 02/2016
1	Cholestasis 05/2013
1	Hepatomegaly 05/2013
1	Retinoblastoma (Glioblastoma, Retinal) 11/2009
1	Ataxia Telangiectasia (Louis Bar Syndrome) 11/2009
1	Liver Failure 10/2008
1	Multiple Myeloma 09/2007
1	Hematologic Neoplasms (Hematological Malignancy) 09/2007
1	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 07/2006
1	Acute Promyelocytic Leukemia 07/2006

Drug/Important Bio-Agent (IBA)

10	Phosphotransferases (Kinase)IBA 01/2020 - 03/2006
10	p38 Mitogen-Activated Protein KinasesIBA 01/2017 - 06/2002
4	CytokinesIBA 11/2020 - 09/2012
4	Protein Kinases (Protein Kinase)IBA 11/2018 - 03/2006
4	Phenobarbital (Luminal)FDA Link 01/2018 - 01/2017
4	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2016 - 06/2005
3	Proteins (Proteins, Gene)FDA Link 01/2019 - 10/2003
3	Mitogen-Activated Protein Kinase 14IBA 02/2007 - 06/2002
2	Taxoids (Taxanes)IBA 11/2018 - 01/2017
2	Pharmaceutical PreparationsIBA 01/2017 - 11/2013
2	Mitogen-Activated Protein KinasesIBA 05/2015 - 02/2012
2	Interleukin-1 (Interleukin 1)IBA 02/2004 - 11/2003
2	LipopolysaccharidesIBA 02/2004 - 11/2003
1	thiamine triphosphorate (TTP)IBA 01/2022
1	Cytokine Receptors (Cytokine Receptor)IBA 11/2020
1	Protein Phosphatase 2 (Protein Phosphatase 2A)IBA 01/2020
1	ChromatinIBA 01/2020
1	Tissue Inhibitor of Metalloproteinase-1IBA 01/2020
1	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 12/2019
1	EnzymesIBA 01/2019
1	GlycogenIBA 01/2019
1	Glycogen Phosphorylase (Phosphorylase, Glycogen)IBA 01/2019
1	Biological ProductsIBA 01/2019
1	IsotopesIBA 01/2019
1	Amino Acids FDA Link 01/2019
1	PhosphoglucomutaseIBA 01/2019
1	ChemokinesIBA 01/2018
1	Erythropoietin FDA Link 01/2018
1	Small Interfering RNA (siRNA)IBA 01/2018
1	Insulin-Like Growth Factor I (IGF-1)IBA 01/2018
1	taxaneIBA 01/2017
1	cabozantinibIBA 01/2017
1	Docetaxel (Taxotere)FDA Link 01/2017
1	Amyloid (Amyloid Fibrils)IBA 01/2017
1	Drug CombinationsIBA 01/2017
1	Estrogens (Estrogen)FDA Link 01/2017
1	LigandsIBA 01/2017
1	Raloxifene Hydrochloride (Evista)FDA Link 01/2017
1	PH 797804IBA 04/2015
1	CaspasesIBA 07/2014
1	Cisplatin (Platino)FDA LinkGeneric 11/2013
1	Cyclin B1IBA 05/2013
1	Proliferating Cell Nuclear Antigen (PCNA)IBA 05/2013
1	Cyclin D1IBA 05/2013
1	TOR Serine-Threonine KinasesIBA 05/2013
1	Interleukin-5 (Interleukin 5)IBA 09/2012
1	OvalbuminIBA 09/2012
1	Immunoglobulin E (IgE)IBA 09/2012
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 09/2012
1	Interleukin-4 (Interleukin 4)IBA 09/2012
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2012
1	A-Form DNA (A-DNA)IBA 11/2009
1	MutagensIBA 11/2009
1	JNK Mitogen-Activated Protein KinasesIBA 10/2008
1	I-kappa B KinaseIBA 10/2008
1	EndotoxinsIBA 10/2008
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 09/2007
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 09/2007
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 03/2006
1	Protein Kinase InhibitorsIBA 03/2006
1	Tyrosine Kinase InhibitorsIBA 03/2006
1	Imatinib Mesylate (Gleevec)FDA Link 03/2006
1	Chelating AgentsIBA 06/2005
1	Hypoxia-Inducible Factor 1IBA 06/2005

Therapy/Procedure

5	Therapeutics 01/2018 - 03/2006
1	Drug Therapy (Chemotherapy) 01/2019
1	Immunotherapy 01/2018
1	Ligation 05/2013